So many in the OB in the 80's and 90's that it is impossible to pick one. After thinking about it I have to go with one I missed, the biggest of them all, the first NC in OB against the Huskers.
We were living in on beach across from hotel with ton of NE fans loaded with cash and convinced they would win, so I sold them my 6 tickets and bet it all on Miami without any points and got 3-1 from them. Made more bets every night until the game. Ended up being my biggest wager ever, beating my total bets on Super Bowl week in DC for the Fins and Redskins in the Perfect Season by 2K.
As much as I love the Cane games, all those 100's made up for missing the game. I taped the game, remember VCR's, and watched it every night that week counting that money. I watch that tape every year and can still feel those bills.