Defensively the biggest question by far imo is Nickel rotation. I really wouldn't be surprised to see any of like 6 names earning heavy rotation at Nickel this season tbh. Then LB to see if Wiley or Bonner win jobs from Chase Smith. Toure is obviously starting. In general we know what the DLine rotation will be. We know what the Outside CBs will be. We mostly know what the safeties will be though that can be impaced depending if Poyser/Fitz/Thornton are primarily the nickel.
Offensively the biggest question by far is OT opposite Cantwell. From there I think the Guard slides into place as the "loser" of the OT competition (likely between Samson and McCoy). Maybe Meriweather ends up winning an OT job though... wouldn't be crazy I guess. I think most likely Meriweather is like the 6th man... I think Buchanan ends up winning a starting OG job (if Meriweather isn't starting OT cause then Samson+McCoy are both OGs). WR and RB is going to be an excellent competition, but we in general know mostly how it'll go. At RB fletcher is the primary. Pringle, Lyle, and Brown are competing for RB2 snaps. At Wr We know Toney and Barkate will probably get the most snaps. Jacobs is likely going to at least get Wr4 type snaps. I think the real competition is Josh Moore, Wingo, and Vaughn for Wr3 type snaps.