OT: UM joins with mj company on concussion treatment drug

[DerekDohrman]

i was researching mj companies and happened to come across this today:

https://www.benzinga.com/pressrelea...-begins-trading-on-the-tsxv-under-symbol-scyb

Scythian is a research and development company committed to finding a solution for the prevention and treatment of concussions and traumatic brain injury with its proprietary Cannabinoid combination.

Scythian's mission is to be the first accepted drug regimen for concussive treatment. Scythian has recently formed a collaboration with the University of Miami and its world renowned neuroscientific team to conduct pre-clinical and clinical trials of its drug regimen. The University of Miami believes that Scythian's scientific approach shows significant promise and differs from previous approaches to treat this growing problem. The collaboration with the University of Miami allows access to their extensive knowledge base in the fields of traumatic brain injury and concussions and allows for Scythian's clinical studies to be undertaken at their world-class facilities.

Gillian A. Hotz, PhD, is leading Scythian's program at the University of Miami. Dr. Hotz is a nationally recognized behavioral neuroscientist and expert in neurotrauma, concussion management, and neurorehabilitation. She has extensive experience in neurocognitive testing. Dr. Hotz has been the co-director of University of Miami Miller School of Medicine's Concussion Program since 1995.

Scythian is also endorsed by Pro Football Legends and the World Boxing Association on its mission.

 

[Cane Dynasty]

CBD is the truth.

 

[OriginalCanesCanesCanes]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

 

[Lokest]

CBD is the truth.

Truth

 

[Cribby]

They should just get some of Russell Wilsons concussion water

 

[DerekDohrman]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

 

[OriginalCanesCanesCanes]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

 

[Cane Dynasty]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

Have you ever smoked weed?

 

[OriginalCanesCanesCanes]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

Have you ever smoked weed?

Irrelevant.

 

[Cane Dynasty]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

Have you ever smoked weed?

Irrelevant.

It's a simple yes or no question.

 

[holdnorth]

****; Kayaa could have continued against Clemson and we would still have Fat Al.

 

[DerekDohrman]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

my point was that the science that documents the efficacy of mj based therapies(and ultimately usage in a market) has been artificially held back. not that the drug approval process isnt long, labor intensive, or fraught with failure

also, this company is based in Canada, as are many other large Cannabis companies, due to canada's supportive stance on mj

 

[OriginalCanesCanesCanes]

It's a simple yes or no question.

So, I'm not answering that question. This isn't about me.

Yes, it's a simple yes or no question, but it's irrelevant to the subject at hand. Not trying to be a jerk, but what difference does it make whether I have or I haven't, for the purposes of this discussion?

 

[OriginalCanesCanesCanes]

Very experimental and years away from human clinical trials, if it ever makes it that far. Drugs at this development stage have a very small chance of making it even to human clinical trials.

But all new modalities start this way, just not many make it.

agreed, but we're entering an entirely new era of potential treatments with mj based therapies becoming legal.

Maybe. Maybe not. There's a big difference between non-FDA approved "remedies" with very little actual science to document their efficacy, and FDA approved drugs that have to go through years of study, animal trials, numerous human trials and finally FDA approval.

Anecdotal evidence is not the same as statistically valid (and significant) human trials that have to meet rigorous scientific and statistical standards for efficacy and safety using double-blind randomized clinical trials.

Don't be surprised if very few, if any, of these cannabinoid "miracles" ever make it to market. There are currently 3 synthetic cannabinoids that are FDA approved as anti-emetics and appetite stimulants. They have very little usage in the marketplace.

my point was that the science that documents the efficacy of mj based therapies(and ultimately usage in a market) has been artificially held back. not that the drug approval process isnt long, labor intensive, or fraught with failure

also, this company is based in Canada, as are many other large Cannabis companies, due to canada's supportive stance on mj

I'm not sure what science you're referring to, but nothing has been held back that I'm aware of. The only science that counts for drug approval, is the science that proves efficacy and safety in comparison to a placebo.

We will see if there are any cannabinoids that emerge as safe and effective treatments for indications other than the ones for which the current synthetic ones are approved, i.e., anorexia associated with weight loss in patients with AIDS and 2nd or 3rd line anti-emesis for patients undergoing chemo.

It's a long road, and will take many years, 5-6 years at least, probably more, with no guarantees that anything will meet the stringent standard of scientific proof required.

 

[UMFarArcher]

i was researching mj companies and happened to come across this today:

https://www.benzinga.com/pressrelea...-begins-trading-on-the-tsxv-under-symbol-scyb

Scythian is a research and development company committed to finding a solution for the prevention and treatment of concussions and traumatic brain injury with its proprietary Cannabinoid combination.

Scythian's mission is to be the first accepted drug regimen for concussive treatment. Scythian has recently formed a collaboration with the University of Miami and its world renowned neuroscientific team to conduct pre-clinical and clinical trials of its drug regimen. The University of Miami believes that Scythian's scientific approach shows significant promise and differs from previous approaches to treat this growing problem. The collaboration with the University of Miami allows access to their extensive knowledge base in the fields of traumatic brain injury and concussions and allows for Scythian's clinical studies to be undertaken at their world-class facilities.

Gillian A. Hotz, PhD, is leading Scythian's program at the University of Miami. Dr. Hotz is a nationally recognized behavioral neuroscientist and expert in neurotrauma, concussion management, and neurorehabilitation. She has extensive experience in neurocognitive testing. Dr. Hotz has been the co-director of University of Miami Miller School of Medicine's Concussion Program since 1995.

Scythian is also endorsed by Pro Football Legends and the World Boxing Association on its mission.

A shame.

Way too late to help Franchise. His squash has been run through a tenderizer.