Clemson got bested at the line of scrimmage on both sides of the ball.
Even with two overtimes, Clemson finished with 34 rushing yards. Travis Etienne had 18 rushes for 28 yards and one touchdown. His longest run was 13 yards. Clemson's 34 yards on the ground were its lowest since 2011 vs. N.C. State.
Clemson allowed 10 tackles for loss, which would rank No. 119 of 123 teams if it was an average-per-game.
Clemson allowed 209 rushing yards, Clemson's most surrendered most since the 2016 national championship game.
Clemson's front didn't do a good job of containing Ian Book when he escaped the pocket to throw or run. Book had 64 rushing yards on 14 rushes. He was only sacked twice, and one was a coverage sack.
"We couldn't contain their quarterback," Swinney said. "We knew third down was going to be critical, and they won that battle. Struggled containing the quarterback all night. He bought time, bought time, bought time. Extended plays and found some guys and made some big runs and scrambles."
Notre Dame was 10-of-19 on third down.
Uiagalelei completed 29-of-44 passes for 439 yards with two passing touchdowns.
It was the most passing yards vs. an AP top 5 team in Clemson history.
His total broke the school freshman record of 435, set by Deshaun Watson.